Synthesis of biocompatible iron oxide nanoparticles as a drug delivery vehicle
| dc.contributor.author | Kansara, Krupa | |
| dc.contributor.author | Patel, Pal | |
| dc.contributor.author | Shukla, Ritesh K. | |
| dc.contributor.author | Pandya, Alok | |
| dc.contributor.author | Shanker, Rishi | |
| dc.contributor.author | Kumar, Ashutosh | |
| dc.date.accessioned | 2025-05-16T10:43:24Z | |
| dc.date.available | 2025-05-16T10:43:24Z | |
| dc.date.issued | 2018-01-01 | |
| dc.description | Open Access | |
| dc.description.abstract | Over the last decade, there has been growing interest in developing novel nanoparticles (NPs) for biomedical applications. A safe-by-design approach was used in this study to synthesize biocompatible iron oxide NPs. The size of the particles obtained was ~100 nm. Although these NPs were significantly (P<0.05) internalized in MCF-7 (human breast adenocarcinoma cell line) cells, no adverse effect was observed in the cells as assessed by cytotoxicity assays (neutral red uptake and 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) and cell cycle analysis. Our data demonstrate the potential of iron oxide NPs as a biocompatible carrier for targeted drug delivery. | |
| dc.identifier.citation | Kansara, K., Patel, P., Shukla, R. K., Pandya, A., Shanker, R., Kumar, A., & Dhawan, A. (2018). Synthesis of biocompatible iron oxide nanoparticles as a drug delivery vehicle. International Journal of Nanomedicine, Volume 13, 79–82. https://doi.org/10.2147/ijn.s124708 | |
| dc.identifier.uri | https://www.dovepress.com/synthesis-of-biocompatible-iron-oxide-nanoparticles-as-a-drug-delivery-peer-reviewed-fulltext-article-IJN | |
| dc.identifier.uri | https://ir.ahduni.edu.in/handle/123456789/4204 | |
| dc.language.iso | en | |
| dc.publisher | Dove Medical Press Ltd | |
| dc.title | Synthesis of biocompatible iron oxide nanoparticles as a drug delivery vehicle | |
| dc.type | Article |