In vitro cytotoxicity of GO–DOx on FaDu squamous carcinoma cell lines
| dc.contributor.author | Shankar, Rishi | |
| dc.date.accessioned | 2025-05-19T05:19:54Z | |
| dc.date.available | 2025-05-19T05:19:54Z | |
| dc.date.issued | 2018-03-15 | |
| dc.description | Open Access | |
| dc.description.abstract | We have synthesized graphene oxide (GO) nanosheets using modified Hummer’s method and conjugated it with doxorubicin (DOx), an anticancer drug. Drug release kinetics from GO–DOx conjugate indicated the drug release at acidic pH. MTT assay performed on FaDu hypopharyngeal cancer cell lines revealed that the GO–DOx nanoconjugate inhibited cell proliferation more efficiently compared with pure DOx. Preliminary results indicate the potential of designed GO–DOx drug conjugate for head and neck cancer. | |
| dc.identifier.citation | Singh, M., Gupta, P., Baronia, R., Singh, P., Karuppiah, S., Shanker, R., Dwivedi, P. D., & Singh, S. P. (2018). In vitro cytotoxicity of GO–DOx on FaDu squamous carcinoma cell lines. International Journal of Nanomedicine, Volume 13, 107–111. https://doi.org/10.2147/ijn.s124891 | |
| dc.identifier.uri | https://www.dovepress.com/in-vitro-cytotoxicity-of-go-dox-on-fadu-squamous-carcinoma-cell-lines-peer-reviewed-fulltext-article-IJN | |
| dc.identifier.uri | https://ir.ahduni.edu.in/handle/123456789/4220 | |
| dc.language.iso | en | |
| dc.publisher | Dove Medical Press Ltd | |
| dc.title | In vitro cytotoxicity of GO–DOx on FaDu squamous carcinoma cell lines | |
| dc.type | Article |