Synthesis and in vitro studies of PLGA-DTX nanoconjugate as potential drug delivery vehicle for oral cancer
| dc.contributor.author | Shanker, Rishi | |
| dc.date.accessioned | 2025-05-16T11:04:00Z | |
| dc.date.available | 2025-05-16T11:04:00Z | |
| dc.date.issued | 2018-01-01 | |
| dc.description | Open Access | |
| dc.description.abstract | Advances in nanotechnology have led to the design of multifunctional nanoparticles capable of cellular imaging, targeted drug delivery, and diagnostics for early cancer detection. We synthesized poly(lactic-co-glycolic acid) nanoparticles encapsulating a model radiosensitizing drug docetaxel accomplishing localized in situ delivery of the sensitizer to the tumor site. The synthesized nanoparticles have been characterized for their physicochemical properties. The in vitro cytotoxicity of drug-loaded nanoparticles has been studied on human tongue carcinoma cell line SCC-9 (ATCC-CRL-1629). | |
| dc.identifier.citation | Gupta, P., Singh, M., Kumar, R., Belz, J., Shanker, R., Dwivedi, P. D., Sridhar, S., & Singh, S. P. (2018). Synthesis and in vitro studies of PLGA-DTX nanoconjugate as potential drug delivery vehicle for oral cancer. International Journal of Nanomedicine, Volume 13, 67–69. https://doi.org/10.2147/ijn.s124995 | |
| dc.identifier.uri | https://www.dovepress.com/synthesis-and-in-vitro-studies-of-plga-dtx-nanoconjugate-as-potential--peer-reviewed-fulltext-article-IJN | |
| dc.identifier.uri | https://ir.ahduni.edu.in/handle/123456789/4209 | |
| dc.language.iso | en | |
| dc.publisher | Dove Medical Press Ltd | |
| dc.title | Synthesis and in vitro studies of PLGA-DTX nanoconjugate as potential drug delivery vehicle for oral cancer | |
| dc.type | Article |